Addictive eating behavior and substance dependence have similar patterns of brain activity, finds a new study from the Rudd Center for Food Policy and Obesity at Yale. The study is published in the Archives of General Psychiatry and is the first to link symptoms of addictive eating behavior with specific patterns of brain activity in both obese and lean individuals.

Previous research has identified similar patterns of brain activity in obese and substance-dependent people, which has led to the theory that some people may be addicted to high-calorie foods, but no previous studies have explored whether lean as well as obese individuals who exhibit symptoms of addictive eating behavior have neural responses similar to those of drug addicts.

In the current study, 48 healthy adolescent women ranging from lean to obese completed the Yale Food Addiction Scale (YFAS), which applies the diagnostic criteria for substance dependence to eating behavior. Next, using brain-imaging procedures such as functional magnetic resonance imaging (fMRI), the study examined the relation of food addiction symptoms, as assessed by the YFAS, with the women’s brain activity in response to food-related tasks. The first task looked at how the brain responded to cues signaling the impending delivery of a highly palatable food (chocolate milkshake) versus cues signaling the impending delivery of a tasteless control solution. The second test looked at brain activity during the actual intake of the chocolate milkshake versus the tasteless solution.

Both lean and obese participants with higher food addiction scores showed different brain activity patterns than those with lower food addiction scores. In response to the anticipated receipt of food, participants with higher food addiction scores showed greater activity in parts of the brain responsible for cravings and the motivation to eat, but less activity in the regions responsible for inhibiting urges such as the desire to drink a milkshake. Thus, similar to drug addicts, individuals exhibiting signs of food addiction may struggle with increased cravings and stronger motivations to eat in response to food cues and may feel more out-of-control when eating highly palatable foods.

According to Ashley Gearhardt, clinical psychology doctoral student at Yale University and lead author, “The findings of this study support the theory that compulsive eating may be driven in part by an enhanced anticipation of food rewards and that addicted individuals are more likely to be physiologically, psychologically, and behaviorally reactive to triggers such as advertising. The possibility that food-related cues may trigger pathological properties is of special concern in the current food environment where highly palatable foods are constantly available and heavily marketed.”

The authors assert that efforts to change the current food environment may be critical to successful weight loss and prevention efforts since food cues may take on motivational properties similar to drug cues. The current emphasis on personal responsibility as the reason for increasing obesity rates may have minimal effectiveness as palatable food consumption may be accompanied with a loss-of-control for individuals exhibiting signs of food addiction.

Source:  Yale University



This was a very well written, if brief article on a subject dear to my heart. I recently wrote a post called, Is Food Addiction the Real Reason You're Fat or can't Loose Weight? on the Addicts Not Anonymous blog, which is pretty much the long, drawn-out version of your article. This article may just be better, considering the short attention span of people today.

Would you say that people with eating disorders or obese people eat a whole lot faster than most people? I'm just curious because of the high brain activity.

hm, interesting, but their are some facts that needs to be cleared more... just saying... :)

I was lean earlier and now I have really gained weight. My eating capacity is the same which means my brain signalling has been. Can anyone suggest why am I putting on weight? EDITOR's note: could be many reasons but our metabolism does slow down as we get older.

Very good article. I think there is quite a close link between substance addiction and other conditions and disorders. It would appear the common factor is the need to feel in control.

I undergo this stage once. You'll be able to surpass it not only on your own willingness but as well as with the help of your family members or people that you live with.

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