Health reasons to avoid pregnancy
Posted by on July 18, 2012 - 4:03pm

We know that many women use contraceptives to prevent unwanted pregnancy often for social, career or economic reasons. In other words, it's not the right time.   There are also health reasons for avoiding or delaying pregnancy.   The Association of Reproductive Health Professional has identified conditions associated with increased risk for adverse health events as a result of pregnancy.  This does NOT mean that all women with these conditions should never get pregnant, but they should have serious discussions with their health providers before they become pregnant, and in some cases, may need to avoid.  Conditions that could lead to a complicated or risky pregnancy, putting the woman at risk include

  • Breast cancer
  • Complicated valvular heart disease
  • diabetes;  insulin dependent with complications
  • Endometrial or ovarian cancer
  • epilepsy
  • Hypertension (high blood pressure)
  • Bariatric Surgery in the past two years
  • HIV/AIDS
  • Ischemic heart disease
  • Malignant liver tumors and certain liver disease
  • Peripartum cardiomyopathy
  • sickle cell disease
  • Solid organ transplant within the past two years
  • stroke
  • systemic lupus
  • platelet mutations
  • tuberculosis

When politicians debate access to contraception and insurance coverage, they need to be aware that there are conditions women may have that put them at high risk for a complicated pregnancy.  Having access to contraceptive methods is critical to planning and/or preventing pregnancy in high risk women.  It's not always about the baby---in these cases,  it is the potential mother!

 

Birth Defects may be linked to high blood pressure, not treatment therapies
Posted by on October 25, 2011 - 9:44am

Women who take angiotensin-converting enzyme (ACE) inhibitors to treat high blood pressure in the first trimester of their pregnancies are at no greater risk of having babies with birth defects than are women who take other types of high blood pressure medication or who take no blood pressure drugs, according to a new study from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality (AHRQ). The study suggests that the underlying high blood pressure itself may increase the risk of birth defects, rather than blood pressure medications taken during the first trimester of pregnancy.

ACE inhibitors are among the most widely prescribed drugs used to treat high blood pressure, particularly for people who also have diabetes. ACE inhibitors are known to raise the rate of birth defects in the second and third trimesters of pregnancy, and one earlier study reported a link between the use of ACE inhibitors and birth defects in the first trimester of pregnancy. But the new AHRQ report, based on a study of a larger population, did not find a unique link between first-trimester ACE inhibitor use and birth defects.

Results of the study, prepared for AHRQ's Effective Health Care Program by the HMO Research Network—a member of AHRQ's Developing Evidence to Improve Decisions about Effectiveness (DEcIDE) Network—are published in the October 18 issue of BMJ.

"Some women of child-bearing age have high blood pressure, and about half of them will get pregnant while taking one or more medications to treat it," said AHRQ Director Carolyn M. Clancy, M.D. "This report should lead to more informed discussions by women, in consultation with their doctors, about the best way to manage their high blood pressure, particularly if they become pregnant."

ACE inhibitors are also used to treat heart failure and to protect some people from diabetes complications. Yet because they work by inhibiting an enzyme in the kidney, physicians counsel caution in taking them in the second and third trimesters of pregnancy, a crucial period of development for the unborn baby. ACE inhibitors carry a "black box" warning from the Food and Drug Administration—that agency's strongest warning—against their use in the second and third trimesters of pregnancy.

A study published in 2006 that examined nearly 30,000 births over 15 years to mothers enrolled in Tennessee's Medicaid system suggested that pregnant women who took ACE inhibitors in the first trimester of pregnancy had babies with birth defects at approximately three times the rate of mothers who were not taking medicines for high blood pressure. But the new AHRQ study—which examined more than 465,000 babies born over 13 years in the Kaiser Permanente Northern California region—found no such correlation. The new report found that birth defects occurred at the same rate among all women with high blood pressure, regardless of whether they took ACE inhibitors, other drugs to treat high blood pressure or no blood pressure drugs.

While the AHRQ study did not conclude that high blood pressure is explicitly to blame for increased birth defects, researchers said that the findings suggest that underlying high blood pressure likely results in increased birth defects. Thus, taking steps to reduce blood pressure before pregnancy—including losing weight and reducing sodium intake—may reduce the risk of birth defects.

Results of the study, prepared for AHRQ's Effective Health Care Program by the HMO Research Network—a member of AHRQ's Developing Evidence to Improve Decisions about Effectiveness (DEcIDE) Network—are published in the October 18 issue of BMJ.