Posted by on May 4, 2011 - 6:56am

If a bone density scan has placed you at risk for osteoporosis, you might want to think twice before starting a bone-building medication as a first course of action. Changing your diet to include more calcium and vitamin D is an effective and less risky strategy that doctors often disregard, according to a recent University of Illinois study published in the journal Nutrients.

Many doctors are quick to prescribe bone-building medication because they believe it's unlikely that people will change their diets, said study co-author Karen Chapman-Novakofski, professor of nutrition at University of Illinois. But these medications have risks, which ironically include an increase in hip fractures and jaw necrosis, and therefore should be used as a last resort when diet and supplements don’t help, she said.

In the study, which analyzed 219 articles in scientific journals, the researchers found that adults who increase their intake of vitamin D and calcium, whether through food or supplements, usually increase their bone mineral density and reduce their risk for hip fracture significantly.

The National Osteoporosis Foundation recommends that adults age 50 and older get a total of 1,200 mg of calcium and 800-1,000 international units (IUs) of vitamin D every day. Karen Plawecki, lead author of the study, said it is possible to consume the recommended calcium without gaining weight. Three glasses of 1 percent or skim milk contain 900 mg of calcium, and many other foods, like soy milk, orange juice, cereal and bread, are often fortified with calcium and vitamin D.

The researchers also noted that following a low-sodium diet seems to have a positive effect on bone density. Click the National Osteoporosis Foundation links below for tips on getting enough calcium and vitamin D.

http://www.nof.org/aboutosteoporosis/prevention/calcium

http://www.nof.org/aboutosteoporosis/prevention/vitamind

Posted by on May 3, 2011 - 10:11am

Most of us get heartburn from time to time. It may come as a burning sensation in the chest, or a bitter taste in the back of the throat. Heartburn is one word people use to describe reflux. It happens when stomach contents come back upwards. Reflux is sometimes painless: You may have trouble swallowing or get a dry cough, perhaps some wheezing.

Occasional reflux episodes are normal. Like millions of Americans, you can manage reflux by avoiding foods that don’t agree with you—things that are fatty, spicy or acidic—or by eating smaller meals. If reflux occurs less than once a week, you can usually cope by making lifestyle changes or using over-the-counter medications.

“We all have a little reflux when we burp or belch,” says Dr. John Pandolfino of Northwestern University. But of the 20 million or more Americans with reflux, about 5% have significant episodes 2 or 3 times per day. When severe events occur this often, it’s not ordinary reflux. It may be gastroesophageal reflux disease (GERD). You may need prescription medications to control it.

Surprisingly, there is very little data addressing sex differences in GERD--and perhaps this is one condition where sex differences only play a small role.  In the few studies that do exist, it appears that the overall incidence of heartburn, regurgitation, non-cardiac chest pain, and wheezing was the same in both sexes though there may be a higher intensity and frequency of symptoms in women but the clinical significance is not clear.   Heartburn is more prevalent during pregnancy and increases in each trimester but that  is believed to be due to anatomic changes such as the pressure of the expanding uterus or, possibility, something to do with progesterone level during pregnancy. It usually goes away after pregnancy.   Obesity and body mass index seems to increase the risk of GERD.

GERD should be taken seriously. Stomach (gastric) contents contain acid needed to digest food. In reflux, these contents wash upward into the esophagus, a slender tube connecting the mouth and the stomach. Because the lining of the esophagus isn’t meant to touch gastric acid, the acid can irritate the lining of the esophagus and lead to bleeding and scarring. In adults, GERD can raise the risk of cancer of the esophagus. And if you have asthma, GERD can make it worse.

As for babies, reflux is common in healthy infants. Most babies outgrow reflux by 13 months, but if they don’t, they too may have GERD.   GERD can harm a child’s ability to feed and grow. It can also increase the risk for inhaling stomach contents into the lungs which could be life-threatening.

People of any age can have GERD. Available medications, whether over-the-counter or prescription, can make the acid in the esophagus less intense. But medications don’t prevent GERD. Surgery can be an option if symptoms are severe and medicine and lifestyle changes don’t seem to help.  The problem isn’t that the stomach makes too much acid. In GERD, the special set of muscles between the esophagus and the stomach is weakened.  Scientists are beginning to look at how nerves receive and send messages to these muscles.

If you have reflux twice or more per week, talk to your health care provider. It’s best to start treatment early to prevent GERD from leading to more serious health problems.

How To Steer Clear of Reflux

Maintain a healthy weight.
Eat smaller meals.
Avoid triggering foods, including alcohol.
Don’t lie down for 3 hours after a meal.
Raise the head of your bed 6 to 8 inches by putting wood blocks under the bedposts.
For an infant, try burping frequently during feeding. Keep the infant upright for 30 minutes after feeding.
If you have reflux twice or more per week, see your health care provider.

Posted by on April 29, 2011 - 8:38am

The more I learn about contaminants in the environment, the more I shop at the local organic market---but it can be expensive.  At a recent lecture held at Northwestern on the Environment and Women's Reproductive Health, I learned that some fruits and vegetables are likely more contaminated than others.  So the key to healthier eating on a budget is to go organic with the 'dirty' foods and still buy conventionally farmed produce that is  least likely to be affected by contamination.

The produce likely to be the most contaminated are:   apples, peaches, pears, bell peppers, celery, nectarines, strawberries, grapes, spinach, lettuce and potatoes.    Splurge a bit on these if you can and go with conventionally farmed products for other fruits and vegetables   Just be sure to  wash them  extra well.   Fruit like melons, oranges and bananas have thick skins that are peeled off, lessening the chance of any toxic effects, and you can save on these.

By the way, the summary of the lecture can be found by going to our home page HERE.

 

Posted by on April 28, 2011 - 4:12pm

An inexpensive instructional program to teach routine newborn care skills to midwives in Zambia resulted in a substantial reduction in the death rate of infants in the first week of life, according to a study funded by the National Institutes of Health and the Bill and Melinda Gates Foundation.

The study, published online in Pediatrics, was conducted by researchers in the Eunice Kennedy Shriver National Institute of Child Health and Human Development’s Global Network for Women's and Children's Health Research.  "Public health officials and policy makers sometimes assume that only expensive, high tech-care can reduce infant mortality," said Linda Wright, scientific director of the NICHD Global Network for Women's and Children's Health Research. "The results of this study show that infant deaths can be prevented in resource-poor countries when only a modest investment is possible."

Each year, roughly 3.6 million infants die worldwide in the first 28 days of life, with the majority dying in the first seven days after birth, the study authors noted. Roughly 98 percent of these deaths occur in developing countries.

The researchers provided midwives from 18 first level delivery facilities in two Zambian cities with instruction in the World Health Organization's Essential Newborn Care Course. The course covers such newborn care basics as routine cleanliness, newborn resuscitation, keeping infants warm and dry, breast feeding, warning signs of potential problems, and dealing with common illnesses. The first level delivery facilities were small hospitals providing women with short term care — usually overnight — and attendance by a midwife, explained the study's senior author, Waldemar A. Carlo, M.D., a researcher in the department of pediatrics at the University of Alabama at Birmingham.

After completing the course, the midwives taught what they learned to other midwives in the facilities where they worked. In turn, these midwives taught what they had learned to the new mothers in their delivery facilities. The researchers compared the experiences of roughly 20,000 infants born in the delivery facilities before the midwives received newborn care training with the experiences of 20,000 infants born after the training period.

Infant mortality during the first seven days of life dropped from 11.5 for every 1,000 births to 6.8 per 1,000 births. The total cost for the training program was $20,244. The researchers estimated that the program saved 97 lives during the study period, amounting to a cost of $208 per life saved.

The researchers also evaluated the study costs in terms of disability-adjusted life years, a measure used by the World Health Organization to estimate the number of years of healthy life lost to premature death or to ill health. By comparing the number of lives saved as a result of the training to the average life expectancy in Zambia, the researchers estimated that a reduction of one disability-adjusted life year cost $5.24.

The researchers estimated that it would cost $14,128 to maintain the program in the future. This cost would include equipment replacement, training manuals, and salary for the program's two part-time nurses.

An earlier study by the NICHD Global Network for Women's and Children's Health Research found that Essential Newborn Care training for birth attendants in six developing countries reduced the rate of stillbirths by 30 percent.

Posted by on April 27, 2011 - 9:27am

Fat talk (women speaking negatively about the size and shape of their bodies) is a popular phenomenon among college women according to a study done by researchers at U of Wisconsin and Northwestern University.  Rachel Salk and Renee Engeln-Maddox interviewed 168 female students at a midwestern U.S. university.  Their work was published in the Psychology of Women Quarterly.

Fat talk goes like this:

Friend #1:  Yuck, I feel sooo fat!"  Friend #2:  "You look great!"  Friend #1:  "You're just saying that!"   Friend #2:  "How would you like to have my hips!"  etcetera...

The researchers found that most women participating in the study engaged in fat talk with their friends, and a third of them did it frequently, even though (according to their Body Mass Index or BMI) they did not meet the definition of overweight.     Those who complained the most, even if they were thin, had greater dissatisfaction with their bodies according to the study.   This group also bought into the media image of the thin, perfect body.      Many of the young women indicated that fat talk made them feel better because "it helps to know that I'm  not the only one who feels bad about my body".

According to the study, the most common response to fat talk was denial that the friend was fat, most typically leading to a back-and-forth conversation where each of the two healthy weight peers denies the other is fat while claiming to be fat themselves.    "Although social support and empathy are usually viewed as psychologically healthy constructs, constant reminders that one's  normal weight or underweight friends also feel fat may not be helpful in the long run.  Such fat talk simply serves to reinforce the thin body ideal and the notion that disliking one's body is normative for women.   Women come to expect this type of talk from their peers and likely feel pressured to engage in it," say the authors.   They further conclude that "fat talk in not about being fat, but rather about feeling fat."

Readers, perhaps instead of fat talk, we should concentrate on wellness talk!   For example, call up a friend and ask her to take a walk or meet you at the gym because it might be fun and a way to meet some health minded guys!!

 

Posted by on April 25, 2011 - 8:57am

Choosing a treatment option for breast cancer can be almost as confusing and frightening as the diagnosis itself. But it doesn’t have to be. A new study from the University of Michigan has found that women make smarter choices about treatments when they receive information and make decisions in small doses rather than all at once.

The researchers wanted to know if asking women to make a series of simpler choices instead of one complex decision would help them better understand the benefits of each treatment. In the study, researchers asked two groups of women to choose between different breast cancer treatment options. The first group got all the information and made all the choices at once. The second group received the same information, but it was divided into two separate choices: First they chose whether to take hormonal therapy, and if they said yes, then they decided whether or not to add chemotherapy.

The women who received the treatment options all at once were more likely to be confused by the information, and more of them chose chemotherapy regardless of whether it would give them a benefit of 1 percent or 5 percent. But the women who made their decisions separately were more likely to choose chemotherapy only if it would give them a larger benefit.

By presenting information piece-by-piece, doctors can help ensure that patients truly understand the benefits before they choose an aggressive treatment like chemotherapy, said Brian Zikmund-Fisher, study author and assistant professor at the University of Michigan School of Public Health. To read the full study, click here.

Posted by on April 21, 2011 - 3:03pm

It has been reported in the past that obesity (body fat mass) is  protective against osteoporosis and fracture.  However, a recent study has documented a high prevalence of obesity in postmenopausal women with fragility fracture.

An international group of researchers has presented research at the European Congress on Osteoporosis & Osteoarthritis that compares the prevalence and location of fractures in obese (Body Mass Index≥30 kg/m2) and non-obese postmenopausal women and examines specific risk factors for fracture.

A history of fracture after age 45 years was observed in 23% of obese and 24% of non-obese women. Nearly one in four postmenopausal women with fractures is obese. The upper arm, ankle and lower leg were significantly more likely to be affected in obese than non-obese women with a prevalent fracture, whereas fractures of the wrist, hip and pelvis were significantly less common than in non-obese women. When compared to non-obese women, obese women with a prevalent fracture were more likely to be current cortisone users, to report early menopause, to report fair or poor general health, to use arms to assist standing from a sitting position, and to report more than two falls in the past year.

The research demonstrates that obese postmenopausal women are almost as likely to fracture as non-obese women, and that poor mobility and increased risk of falls may play an important role. The findings have significant public health implications in view of the rapidly rising numbers of obese people in the population.

 

Posted by on April 20, 2011 - 9:09am

Now that so many women are balancing school, family, and work, it's hard to find time to stand up for women's causes.   But it is important and it does work.   Recently a prominent surgeon wrote a Valentine's Day editorial about the mood enhancing effects of semen on women during unprotected sex.   He cited a research study done in 2002 that reported that female college students who had had unprotected sex were less depressed that those who used condoms. It implied that compounds in semen have antidepressant effects.  He goes further to imply sex without condoms may be a nice Valentine's present. WHAT?#?#

The reaction from female doctors and especially female surgeons was almost immediate and full of outrage.   Guess what?  The surgeon (who was president-elect of the American College of Surgeons) submitted his resignation with little fuss, despite his many accomplishments and past support for women.     Even he must have felt that he went way over the line.   If you want to read the New York Times report on this incident, click here.

Even better, think about what is important to you as a woman related to health and if you find some shortcomings, find the time to speak out!

Posted by on April 19, 2011 - 2:05pm

Today, over 250 health professionals attended our monthly forum on the environment and reproductive health and I am certain that no one left the room doubting that the chemicals we are exposed to at home, at work, in our food, and in the air are harmful to reproductive health.   Dr. Tracey Woodruff from the Program on Reproductive Health and the Environment from UC SF was our outstanding speaker.   A summary of her presentation will be posted in a few days on this blog but if you are concerned about the effect of chemicals on you and your family, especially children, she directed us to a brochure her institution produced that is available free on line that is filled with helpful hints.    Click on Toxic Matters to download a free copy and check back in a few days for our summary article.

Posted by on April 18, 2011 - 2:52pm

Male fetuses most vulnerable to alcohol.

Exposure to alcohol in the womb doesn’t affect all fetuses equally. Why does one woman who drinks alcohol during pregnancy give birth to a child with physical, behavioral or learning problems -- known as fetal alcohol spectrum disorder -- while another woman who also drinks has a child without these problems?

One answer is a gene variation passed on by the mother to her son, according to new Northwestern Medicine research. This gene variation contributes to a fetus’ vulnerability to even moderate alcohol exposure by upsetting the balance of thyroid hormones in the brain.  The Northwestern Medicine study with rats is the first to identify a direct genetic mechanism of behavioral deficits caused by fetal alcohol exposure. The study is published today in the FASEB Journal.

“The findings open up the possibility of using dietary supplements that have the potential to reverse or fix the dosage of the thyroid hormones in the brain to correct the problems caused by the alcohol exposure,” said Eva E. Redei, senior author of the study and professor of Psychiatry at Northwestern University Feinberg School of Medicine.

“In the not-too-distant future we could identify a woman’s vulnerability to alcohol if she is pregnant and target this enzyme imbalance with drugs, a supplement or another method that will increase the production of this enzyme in the hippocampus, which is where it’s needed,” Redei said.

Efforts to educate pregnant women about the risks of alcohol have not changed the percentage of children born with fetal alcohol spectrum disorder, Redei noted.

The gene involved, Dio3, makes the enzyme that controls how much active thyroid hormone is in the brain. A delicate balance of the thyroid hormone is critically important in the development of the fetal brain and in the maintenance of adult brain function. Too much of it is as bad as too little.

When males inherit this variation of the Dio3 gene from their mother, they don’t make enough of this enzyme in their hippocampus to prevent an excess of thyroid hormones. The resulting overdose of the hormones makes the hippocampus vulnerable to damage by even a moderate amount of alcohol. The rat mothers in the study drank the human equivalent of two to three glasses of wine a day. Their male offspring showed deficits in social behavior and memory similar to humans whose mothers drank alcohol.

The alcohol causes the problem by almost completely silencing the father’s copy of the Dio3 gene in animals whose mother has the gene variation. As a result, the offspring don’t make enough of this enzyme, disrupting the delicate balance of the thyroid hormone levels. This is an example of an interaction between genetic variation in the DNA sequence, and epigenetics, which is when the environment, such as alcohol in utero, modifies the DNA.

“The identification of this novel mechanism will stimulate more research on other genes that also influence alcohol-related disorders, especially in females,” said Laura Sittig, the lead author of the study and a graduate student in Redei’s lab.

In the study, the rats’ social behavior was measured by putting a pup into a cage with an adult. Normal adult behavior is to lick and smell the pup. The adults exposed to alcohol in utero, however, interacted with the pup half as much as normal. They also forgot where to navigate in a maze that evaluated spatial memory.

“These results show they had social and memory deficits,” Redei said. “This indicates the damage to the hippocampus from the alcohol exposure.”

by Marla Paul, health sciences editor, Northwestern U.

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